Regional truck driving jobs in St. Louis County, Missouri, offer CDL drivers excellent routes, dependable pay, and frequent home time. The area supports a wide range of freight with major highways running through the region.

• Work near St. Louis metro with steady freight opportunities
• High-mileage lanes with home weekly options
• Strong logistics presence along I-70, I-64, and I-270
• Top carriers offer medical benefits, PTO, and retirement plans
• Openings for dry van, reefer, and hazmat endorsements

Apply now and discover regional CDL jobs that offer balance and reliability in St. Louis County.