Regional Truck Driving Jobs In Missouri

Missouri
Regional truck driver beside a semi-truck in Missouri

Discover great opportunities for regional truck driving jobs in Missouri, where central U.S. location and strong highway access keep freight moving all year long.

  • Missouri drivers enjoy high demand along I-70, I-44, and I-55 freight corridors.
  • Most regional routes offer weekly or even multiple home days per week.
  • Top hiring cities include St. Louis, Kansas City, and Springfield.
  • Local fleets handle consumer goods, agriculture, and manufacturing freight.
  • Stable routes and rising wages make Missouri ideal for both new and experienced CDL drivers.

Drive Your Career Forward in Missouri

From metro hubs to rural routes, regional CDL jobs in Missouri offer consistent schedules, solid pay, and opportunities for long-term growth. Drive with leading carriers that value your time and experience.

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Click below to view the latest regional CDL job openings across Missouri.

Available Regional Truck Driving Jobs in Missouri

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Regional Jobs in Missouri Listing

CDL A Regional Drive-No Experience OK

DriveLine Solutions

St. Louis, Missouri $1,400 a week Full-time Posted: 2025-05-20
Grow your career with us as a Class A Regional Driver. Benefit from our strong company reputation, health incentives, and opportunities for professional growth in the transportation industry.
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CDL A Regional Driver - Recent Grads

Butler Transport, Inc

Branson, Missouri $0.60 per mile Home time Posted: 2025-07-03
Be a part of the reputable Butler team and experience career growth opportunities. Drive consistent routes, with great mileage, and job security. Join us for a professional and rewarding driving career.
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Owner/Operator- Class A CDL Driver- OTR-Regional- Dry Van

Dry Creek Logistics

Branson, Missouri $5,000 - $6,000 a week Full-time Posted: 2025-07-03
Grow your career with our reputable 100% owner-operator company offering regional runs, OTR services, and dedicated customer freight. Enjoy fuel discounts, insurance, and professional development opportunities.
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Owner Operator Truck Driver Regional & Local OTR Loads

NRL Carrier

Branson, Missouri $7,000 a week Full-time Posted: 2025-07-03
NRL Carrier, a locally owned logistics company, prioritizes driver satisfaction with high-paying loads and a respectful work environment. With opportunities for career growth and professional development, drivers can thrive in a diverse and multilingual team.
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Explore Regional truck driving jobs across Missouri.