Regional Truck Driving Jobs In Missouri
Discover great opportunities for regional truck driving jobs in Missouri, where central U.S. location and strong highway access keep freight moving all year long.
- Missouri drivers enjoy high demand along I-70, I-44, and I-55 freight corridors.
- Most regional routes offer weekly or even multiple home days per week.
- Top hiring cities include St. Louis, Kansas City, and Springfield.
- Local fleets handle consumer goods, agriculture, and manufacturing freight.
- Stable routes and rising wages make Missouri ideal for both new and experienced CDL drivers.
Drive Your Career Forward in Missouri
From metro hubs to rural routes, regional CDL jobs in Missouri offer consistent schedules, solid pay, and opportunities for long-term growth. Drive with leading carriers that value your time and experience.
Apply Now!
Click below to view the latest regional CDL job openings across Missouri.
Regional Jobs in Missouri Listing
CL A Dedicated Regional Home W/Ends-1750-2800/WK
The Wick Transport
This job description is for Class A drivers who value consistency, competitive pay, and being home most weekends. This job offers a dedicated regional run with the convenience of being home weekly and home for the weekends 80% of the time. The position has an average weekly pay of $2000 and requires drivers to handle 100% touch freight (average weight 1-18 lbs), although inventory and stocking will not be part of the job. A stylish and well-kept truck fleet of Freightliners and Internationals will be at your disposal.
A dedicated regional route for consistency
Competitive pay starting at $.70-$.80 CPM
Weekly average of $2000 in earnings
Visits home every week and 80% of weekends
Average annual pay of $104K, with the range being $100-$108K/Yr
100% touch freight role with avoidance of inventory and stocking responsibilities
A chance to drive modern, automatic transmission Freightliner and International trucks
A pet-friendly and companion-friendly policy after training is complete
Incremental pay raises every 6 months
Additional benefits such as $25/Stop and $240 Trailer Unload
Paid training at a rate of $200/day for 5 days
A comprehensive benefits package including PTO, medical, dental, and 401K after 60 days
Must possess 3 months verifiable Class A driving experience in the last three years
No more than 2 non-serious moving violations in the last 12 months and no more than 3 in the last 36 months
No more than one serious moving violation in the last 12 months
No more than 2 preventable accidents in the last two years
No termination from last job due to safety reasons
Cannot have ever failed or refused a DOT drug test
Don't miss this opportunity if you're a Class A driver interested in being home most weekends while earning over $100K a year. Submit your resume today!
This regional job offers:
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CDL-A Drivers: Get Pay Protection on Regional Runs + Home Weekends!
Millis Transfer
As a Midwest Regional Driver for Millis Transfer, you will be responsible for driving our top quality equipment, taking advantage of our pay protection program, and enjoying the perks of our performance bonus system. With the unique opportunity to get home every weekend while still earning an average of $1600 per week (gross pay plus 401k contribution), Millis Transfer presents an exciting, high-paying job offer that includes weekly mileage based bonuses, a rider policy, and orientations in multiple locations.
An average weekly earning of $1600 (gross pay plus 401k contribution).
The opportunity to get home every weekend.
A Pay Protection Program that ensures your weekly paycheck's safety.
Performance Bonus – with the capacity to earn up to 7cpm, based on weekly mileage.
Orientations in MULTIPLE LOCATIONS!
Up to 5 weeks of paid vacation - based on your longevity with Millis.
A complete benefits package inclusive of Health, Dental Vision, Short Term Disability, 401(k), and Life Insurance.
Paid Orientation.
A flexible Rider Policy.
A Valid Class-A CDL License.
At least 6 months Over The Road Experience.
A good driving record for the last 5 years.
The ability to pass a background check.
Millis Transfer is a multi-safety award winner recognized by customers, state associations, and the Truckload Carriers Association. Don't hesitate! Call Millis Transfer Today at (888) 528-1390.
This regional job offers:
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Millis Transfer is a multi-safety award winner recognized by customers, state associations, and the Truckload Carriers Association. Don't hesitate! Call Millis Transfer Today at (888) 528-1390.
Car Hauler * Good Home Time * Preferred Lanes * MO Regional
JMN Transportation Inc
JMN is currently on the lookout for experienced 9/10 Car Haulers for their Missouri regional operations. If you're someone who values state-of-the-art equipment, easy-to-use spin straps, and regional routes coupled with fantastic benefits, this could be the perfect role for you. JMN extends an opportunity for you to join their inclusive and supportive family.
Late model equipment
EZ spin straps
Regional lanes
Annual Bonus Opportunities
401(K) with Company Match
Paid Vacations
Paid Holidays
Paid Time Off
Daily Per Diem
Paid Life Insurance
Multi Drop Pay
Must be 23 years of Age or Older
Valid Class A CDL
Minimum of 1 year Car Hauling experience
Join the JMN Family and take your career to new heights with this opportunity!
This regional job offers:
Benefits you will have:
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Join the JMN Family and take your career to new heights with this opportunity!
CDL A Regional Drive-No Experience OK
DriveLine Solutions
This is a position for a Class A Regional Driver, accommodating for those without experience. The role entails operating reefer trailers, delivering groceries on a regional round trip route from Moberly, MO, to various cities such as Saint Louis, MO, Des Moines, IA, and Columbia, MO. The job ensures home time every week and work every holiday excluding Thanksgiving and Christmas. The mode of freight includes drop and hook as well as live load. Potential weekly earnings stand at $1,400.
Weekly earnings of $1,400.
Home time every week.
Regional round trip grocery delivery.
Work holidays excluding Thanksgiving and Christmas.
Operating reefer trailers.
Drop and hook, as well as live load delivery modes.
Health incentives including medical, dental, and vision coverage.
Provided PTO.
401k retirement plan.
Must be at least 21 years of age.
No prior experience necessary.