OTR Trucking Jobs In South Carolina

South Carolina

South Carolina's booming port and manufacturing sectors make it a major logistics hub, creating a constant need for OTR trucking jobs in South Carolina. The Port of Charleston is one of the busiest on the East Coast, generating massive volumes of container freight, especially for the state's massive automotive and tire manufacturing plants. OTR drivers are essential for moving these goods inland and along I-95 and I-26, connecting the Southeast to the rest of the country. The state's strong economy ensures a steady flow of high-rate freight.

The demand for OTR professionals in the Palmetto State is exceptionally high, driven by the state's massive economic growth. Carriers based here offer competitive pay and excellent benefits, recognizing the value of efficient long-haul transportation. If you're an OTR driver looking for a stable base with consistent miles, a strong industrial economy, and a key role in connecting the East Coast, explore the top OTR trucking opportunities in South Carolina today. Your dedication to the road is highly valued here.

Featured Opportunities

⭐ FEATURED

Empire National

Based in Chicago, IL

26FT Box Truck Owners

$4,000 - $8,000 a week Owner Operator

✓ Regional & OTR Routes ✓ Fuel discount ✓ No Forced Dispatch ✓ Weekly Settlements

Apply now →

⭐ FEATURED

TRANSGEORGIA LLC

Based in Chicago, IL

Owner Operators Needed – Cargo vans, sprinters & Large Box Trucks

$5,811 - $6,405 a week Owner Operator

✓ Consistent Work Next-Day Pay ✓ No Forced Dispatch ✓ Referral program Apply now →

Available OTR Jobs in South Carolina

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Current OTR Job Listings for South Carolina

CDL-A OTR Truck Driver | High Miles

ASAP TRANS CORP

Posted: 2026/01/03

Charleston, South Carolina $2,200 - $4,000 a week Local - Home Daily

Work in Wisconsin with GFL Environmental as a local truck driver, where the state's extensive logistics network and high freight volume make it an ideal place for efficient operations. The well-maintained infrastructure supports timely deliveries throughout the region, enhancing your ability to excel in your role. Additionally, enjoy competitive benefits, including paid time off and a robust health insurance package, all while contributing to sustainable waste management solutions in your community.

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