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CDL Jobs in South Carolina

Find Local, Regional, OTR & Owner Operator Truck Driving Jobs in South Carolina

500+
Active Jobs
$75K+
Average Salary
50+
Companies
100+
Owner Operator Jobs

CDL jobs in South Carolina are in high demand, supported by the state’s growing economy and strong freight corridors. With I-20, I-26, I-77, and I-95 connecting Columbia, Charleston, and Greenville, CDL drivers have excellent access to Southeast and national markets.

CDL holders in South Carolina can work in port freight, automotive, agriculture, and retail distribution. Local delivery, regional trucking, OTR, and specialized jobs such as tanker and flatbed hauling are all available.

For drivers seeking steady pay, reliable freight, and career growth, South Carolina CDL jobs provide some of the strongest opportunities in the Southeast.

Why Choose CDL Truck Driving Jobs in South Carolina:

  • Port Access – Charleston drives international freight demand
  • Diverse CDL Roles – Local, regional, OTR, tanker, and flatbed
  • Strong Industries – Automotive, agriculture, and retail
  • Year-Round Opportunities – Steady loads across the state
  • Competitive Earnings – Reliable pay with career advancement

Explore CDL Truck Driving Jobs Across South Carolina

Discover statewide opportunities — Local, Regional, OTR, and Owner Operator CDL jobs in South Carolina.

Local Jobs

Home daily CDL routes near you.

Regional Jobs

Weekly home-time & shorter runs.

OTR Jobs

Long-haul routes across the country.

Owner Operator

Run your own business, maximize pay.

Latest CDL Job Listings in South Carolina

CDL Class A Tanker Driver

DHL

Laurens, South Carolina From $328 a day Full-time
Operate regional routes as a CDL Class A Tanker Driver with DHL in Laurens, SC 29360, where the strong infrastructure and optimal freight density ensure you can maximize your earnings. Enjoy a minimum pay of $328 a day while navigating well-maintained roads that connect seamlessly throughout the region. Gain valuable experience with paid training and orientation as you safely transport liquid chemicals and contribute to the efficiency of vital supply chains.
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Explore Regional, OTR, Owner Operator & Local Jobs

Owner Operators with 24-26' Box Trucks

Hurdle 2 Success

Greenville, South Carolina $3,400 - $4,700 a week Owner Operator
Excel as a driver in South Carolina with Hurdle 2 Success, where exceptional opportunities await independent contractors in a thriving freight market. In South Carolina, take advantage of a robust compensation structure that can reach an impressive $4,700.00 per week, supporting your entrepreneurial spirit. Experience a dynamic environment where you can build your business while accessing reliable delivery routes. Join a company that prioritizes your success and provides unparalleled assistance in navigating the opportunities within South Carolina’s business-friendly landscape.
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Local Driver

Superior Transportation

North Charleston, South Carolina yearly Local
Establish long-term driving profession with company committed to driver success and industry leadership. Professional progression opportunities include specialized training and skill enhancement programs. Growth-oriented environment with pathways for increased responsibility and expertise recognition.
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Truck Driver Semi Local

21st Century Personnel

Columbia, South Carolina $0.60 - $0.70 per mile Local
Seize the opportunity for professional growth and long-term success with our semi-local Class A driving position. Your career trajectory benefits from a starting pay of .60-.70 cpm, 401k, and excellent benefits. Join a team focused on your future, offering a predictable schedule and opportunities for advancement.
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Driver CDL Class A

Southern Fuelwood Company

Newberry, South Carolina yearly Local
Fuel your career trajectory and seize long-term opportunities for professional development with us. Grow exponentially alongside industry innovators who pave the way for success. Elevate your skills, expand your horizons, and chart a path to a future where possibilities are endless.
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Explore Jobs Across South Carolina

Explore CDL truck driving jobs across South Carolina.

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CDL Jobs in Other South Carolina Cities

CDL Jobs in Laurens

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Trucking Companies Hiring in South Carolina

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Start Your CDL Driving Career in South Carolina

Explore hundreds of CDL truck driving opportunities across South Carolina. Whether you’re a new driver or an experienced pro, find jobs that match your skills, pay goals, and preferred routes.

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